The topic of this undergraduate thesis is to develop the procedure of CNC programming for end milling operation, specifically for the aluminum alloys using all the knowledge about the mentioned material and its machinability. In first part of this thesis aluminum alloys is described in detail, its properties and applications. Subsequently, there is given an overview of aluminium alloys, their classification, properties and applications. Also, the machinability of aluminum alloys is described in detail with special emphasis on indicative factors that determine the machinability. Methods of application of SHIP and its types and finally the basics of CNC programming are all presented, advantages and disadvantages of CNC machines, their characteristics, main and auxiliary functions are listed. Furthermore, programming in ShopMill is briefly explained. The second part of this thesis is the practical part which involves manufacturing aluminum alloys product using knowledge of material. The aim of this thesis is to explore the possibilities and limitations of aluminum alloys, a material with such wide application in various industries (construction, aerospace, etc.). In practical part of this thesis, it was necessary to write G-code and program it in ShopMill. This undergraduate thesis greatly consolidates the knowledge of aluminum alloys and enabled its specific application, i.e., the production of workpieces.